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How do you know you are in menopause? And it can still be years before your last menstrual period. Some common, normal signs include irregular periods, hot flashes, vaginal dryness, sleep disturbances, and mood swings—all results of unevenly changing levels of ovarian hormones (estrogen) in your body. Read more about how you 'll know you 're near menopause.
How long does it take for HRT to leave your system? When to stop taking HRT Most women are able to stop taking HRT after their menopausal symptoms finish, which is usually two to five years after they start. Gradually decreasing your HRT dose is usually recommended, rather than stopping suddenly.
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Where is the best place to put my estrogen patch? You should apply estradiol patches to clean, dry, cool skin in the lower stomach area, below your waistline. Some brands of patches may also be applied to the upper buttocks or the hips.
How long does it take to feel the effects of hormone replacement therapy? It usually takes a few weeks before you will feel the initial benefits of HRT and up to three months to feel the full effects. It may also take your body time to get used to HRT. When treatment begins you may experience side effects such as breast tenderness, nausea and leg cramps.

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