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Hyperactivity Disorder Combined Type.

That is to say, a carrier of two APOE 4 alleles is more likely to develop late-onset Alzheimer's disease (LOAD) than a carrier of only one APOE 4 allele, and at an earlier age (Corder et al.

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TOMM40 and ApoE proteins are, therefore, of particular interest for Alzheimer's disease.

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All eight patients enrolled in the study received study medication and had at least one post baseline efficacy assessment of the primary efficacy variable, MADRS.

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We show evidence that SNCA can be regulated via the 5'untranslated region (5'UTR) of its transcript, which we modeled to fold into a unique RNA stem loop with a CAGUGN apical loop similar to that encoded in the canonical iron-responsive element (IRE) of L- and H-ferritin mRNAs.

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